News and information about the National Data Bank for Rheumatic Diseases (NDB) and arthritis and rheumatology research. Written for NDB participants and anyone with a rheumatic disease.
More dollars for research, but fewer new drugs
"Total U.S. investment in biomedical research has more than doubled in a decade, rising from $37 billion annually in 1994 to more than $94 billion by 2003, a new report shows. The statistic should please most Americans: According to a second report, almost 80 percent of people consistently support medical research as one of the nation's top spending priorities.... And yet the study did uncover one sobering statistic: Despite the doubling in research investment, the number of new drugs receiving Food and Drug Administration approval actually dropped during the past decade, from an average of 35.5 a year between 1994-1997 to only 23.3 annually by 2001-2004." - from MedlinePlus
¶ Monday, September 26, 2005
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Friday, September 23, 2005
FDA rejects injectable cox-2, parecoxib
"U.S. regulators have rejected Pfizer Inc.'s application to market an injectable drug very similar to its withdrawn Bextra arthritis pill, the company said on Tuesday....The injectable drug is sold overseas, including in the European Union, mostly under the brand name Dynastat. European regulators have said benefits of that form of the drug, used to control pain after surgery, outweigh its potential risks." - from Yahoo! Health News
¶ Friday, September 23, 2005
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Thursday, September 22, 2005
Study: Oil exposure increases RA risk
"Scientists said Wednesday the results of a new study indicate occupational exposure to motor oil significantly increases the chances a person will develop rheumatoid arthritis. 'According to the results of our study, mineral oils (in particular, hydraulic oil and motor oil) appear to be associated with a particular high risk of' two different forms of rheumatoid arthritis, a team of Swedish researchers led by Lars Klareskog of the Karolinska Institutet in Stockholm wrote in the Sept. 23 issue of Arthritis Research and Therapy." - from MedlinePlus
¶ Thursday, September 22, 2005
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Monday, September 19, 2005
Abatacept may be newest drug in anti-RA arsenal
"People with rheumatoid arthritis that doesn't respond to any of the currently available treatments may soon have a new therapeutic option. A new medication called abatacept (brand name, Orencia), more than doubled the odds that someone with difficult-to-treat rheumatoid arthritis had at least a 20 percent improvement in symptoms, according to a new study.....Abatacept works by blocking a signal that fully activates the immune system's T-cells. Because the drug modifies the response of the immune system, the risk of infection is potentially increased." - from HealthDay
¶ Monday, September 19, 2005
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Tell your doctor about your alternative meds
"The popularity of complementary and alternative medicine is on the rise, with more than one-third of U.S. adults using at least one these treatments, according to a recent report by the Institute of Medicine. And if you're like most proponents of these treatments, you probably don't mention them to your primary-care physician. You may think it's not important or you might just forget. Or, you might think your doctor won't approve." - from HealthDay
¶ Monday, September 19, 2005
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Wednesday, September 07, 2005
RA becoming less severe, study says
"Scientists have some good news for rheumatoid arthritis sufferers: The disease is becoming milder, with less severe symptoms and less functional disability compared to that experienced by arthritis patients in the past. The exact reasons for the decline in rheumatoid arthritis severity remains unclear, Dutch researchers say, but may stem from the more aggressive drug therapies that are now available to patients." - from HealthDay
¶ Wednesday, September 07, 2005
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WELCOME!
The National Data Bank for Rheumatic Diseases (NDB) performs unique clinical
research in rheumatoid arthritis, osteoarthritis, fibromyalgia, lupus and other
rheumatic diseases, designed to improve the treatment and outcomes of these conditions.
The NDB is the largest patient-reported research databank for rheumatic diseases in
the United States. We report to the rheumatology community in peer-reviewed journals
and at the major scientific conferences.
You are invited to join us in our work, either as a person with a rheumatic disease
who would like to join the study, or as a physician or researcher who wants to help
and use our databank and research services, including data collection tools and database support.
The NDB is an independent, non-profit research group.
All information within the NDB web log, including links away from this site,
is for educational purposes only. Nothing presented here should be taken to be medical advice.
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You can make a difference in Arthritis Research! Consider volunteering a bit of your time for the improvement of treatment and outcomes of rheumatic diseases.
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