Arthritis Internet Registry

The Arthritis Internet Registry (AIR) is groundbreaking study to use the power of the internet to create a community of arthritis patients for discovery research. AIR recognizes the importance of research to improve the lives of arthritis patients. At the same time, we recognize the needs of patients to discuss their disease with other patients. The purpose of AIR is to bring together a community of arthritis patients -- particularly those with rheumatoid arthritis (RA) -- to enable discovery research and social networking via the internet.

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Initially, AIR will focus on enrolling patients, collecting relevant clinical data, and collecting blood biospecimens for discovery research. Such research includes understanding genetic predictors of RA risk, cardiovascular complications and response to RA therapies. As AIR grows, we will add social networking capabilities to allow arthritis patients to communicate with other arthritis patients about their disease.

AIR is a partnership between leading academic researchers (see below) and Quest Diagnostics. Drs. Kaleb Michaud (National Data Bank for Rheumatic Diseases) and Robert Plenge (Harvard Medical School, Brigham and Women's Hospital) led the pilot study.

Meet the AIR Researchers

Kaleb Michaud, PhD

Kaleb Michaud, PhD

Dr. Michaud is an Assistant Professor of Medicine in the Section of Rheumatology & Immunology at the University of Nebraska Medical Center in Omaha. Since 2001 Dr. Michaud has provided statistical analysis and research project guidance to the National Data Bank for Rheumatic Diseases, the largest non-administrative, observational open-cohort study of patients with rheumatoid arthritis (RA) in the world. In addition, he is the principle investigator for the Rheumatoid Arthritis Investigators Network (RAIN) database and is a researcher with the Veterans Affairs RA (VARA) registry.

His primary interests are in the pharmacoepidemiology, burden of disease, mortality, and cost-effectiveness of treatment for people with RA. He currently receives support from an Arthritis Foundation's New Investigator Award, has been appointed an Adjunct Affiliate at Stanford University’s Center for Primary Care and Outcomes Research, and has been invited to the Young Investigators Initiative Workshop Program, US Bone & Joint Decade.


Peter K. Gregersen, MD

Dr. Gregersen is Director, Center for Genomics & Human Genetics, The   Feinstein Institute for Medical Research and Professor, Molecular Medicine, Hofstra North Shore-LIJ School of Medicine. Originally trained  as a rheumatologist, Dr. Gregersen, has been working in the area of genetics for more than two decades and has led several major international consortia to study the genetics of rheumatoid arthritis, systemic lupus, myasthenia gravis, myositis and other autoimmune disorders. He has spearheaded the development of robotic biorepository and informatics resources to support his studies. Visit his lab's webpage.

The Royal Swedish Academy of Sciences selected Dr. Gregersen to receive the prestigious Crafoord prize for his genetic research in rheumatoid arthritis. The prize was presented in Stockholm by the king of Sweden on May 2, 2013.

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