Medical Schools
MD, Baylor College of Medicine (1999)
Graduate Schools
PhD, University of Colorado Denver (2010)
Undergraduate Schools
BA, University of Texas–Austin (TX) (1994)
Emory University Program (2000)
Residency Program
Emory University Program, Internal Medicine (2002)

Washington University/Barnes-Jewish Hospital/St. Louis Children’s Hospital, Internal Medicine - Rheumatology (2005)


Assistant Professor of Medicine, Rheumatology, University of Colorado

Staff Physician, Denver Veterans Affairs Medical Center


Dr. Caplan's major interest is in pharmacoepidemiology and he has focused on the toxicities of therapies for rheumatoid arthritis (including use of steroids) as well as the development of autoimmune pulmonary disease. His expertise extends to use of large administrative datasets and the creation of registries. He has worked with the National Data Bank for Rheumatic Diseases, and is an investigator with the Veterans Affairs Rheumatoid Arthritis registry and the Program to Understand the Longterm Outcomes in SpondyloARthritis (PULSAR) registry.

Recent NDB research

Cannon GW, DuVall SL, Haroldsen CL, Caplan L, Curtis JR, Michaud K, et al. Persistence and Dose Escalation of Tumor Necrosis Factor Inhibitors in US Veterans with Rheumatoid Arthritis.J Rheumatol. 2014 Aug 15. pii: jrheum.140164. PubMed link
Kerr G, Aujero M, Richards J, Sayles H, Davis L, Cannon G, Caplan L, Michaud K, Mikuls T. Associations of hydroxychloroquine use with lipid profiles in rheumatoid arthritis: Pharmacologic implications. Arthritis Care Res (Hoboken). 2014 Apr 1. doi: 10.1002/acr.22341. PubMed link
Caplan L, Wolfe F, Michaud K, Quinzanos I, Hirsh JM. Health literacy is strongly associated with functional status among rheumatoid arthritis patients: A cross-sectional study. Arthritis Care and Research. 2014 Apr;66(4):508-14. doi: 10.1002/acr.22165. PubMed link
Sokolove J, Johnson DS, Lahey LJ, Wagner CA, Cheng D, Thiele GM, Michaud K, et al. Rheumatoid factor as a potentiator of anti-citrullinated protein antibody-mediated inflammation in rheumatoid arthritis. Arthritis Rheumatol. 2014 Apr;66(4):813-21. doi: 10.1002/art.38307. PubMed link
Mikuls TR, Padala PR, Sayles HR, Yu F, Michaud K, Caplan L. et al. Prospective study of posttraumatic stress disorder and disease activity outcomes in US veterans with rheumatoid arthritis. Arthritis Care and Research. 2013:Vol. 65(2):227-3 PubMed link
Masri KR, Shaver TS, Shahouri SH, Wang S, Anderson JD, Busch RE. et al. Validity and reliability problems with patient global as a component of the ACR/EULAR remission criteria as used in clinical practice. Journal of Rheumatology. 2012: 39(6):1139-45 PubMed link
Anderson J, Caplan L, Yazdany J, Robbins ML, Neogi T, Michaud K. et al. Rheumatoid Arthritis Disease Activity Measures: American College of Rheumatology Recommendations for Use in Clinical Practice. Arthritis Care and Research. 2012:64(5):640-647 PubMed link
Anderson JK, Zimmerman L, Caplan L, Michaud K. Measures of rheumatoid arthritis disease activity. Arthritis Care Res. 2011;63(S11):S14-S36.
Shahouri SH, Michaud K, Mikuls TR, Caplan L, Shaver TS, Anderson JD, et al. Remission of rheumatoid arthritis in clinical practice: Application of the ACR/EULAR 2011 remission criteria. Arthritis Rheum. 2011;63(11):3204-15. PMCID: 3202065. PubMed link
Mikuls TR, Fay BT, Michaud K, Sayles H, Thiele GM, Caplan L, et al. Associations of disease activity and treatments with mortality in men with rheumatoid arthritis: results from the VARA registry. Rheumatology. 2011;50(1):101-9. PMCID: 3108313. PubMed link